Ray Peat on growth hormones

January 3, 2026

Critical views on long-term estrogen therapy

"Constance Martin writes in her textbook of endocrine physiology (1976) that estrogens are not useful when administered over long periods of time.... MR Urist (in Biochemistry and Physiology of Bone, Vol. 2, ed. by GH Bourne, 1972 edition) says that estrogen does not restore bone mass to an extent detectable by X-rays, that an excess of growth hormone can worsen the disorder, and that estrogen stimulates the secretion of growth hormone."

Nutrition for Women

LH, growth hormone and the role of prolactin in stress and estrogen

"LH (luteinizing hormone) increases when progesterone or testosterone is lacking, and growth hormone and prolactin (which are closely linked in evolution) both increase in a variety of stressful situations as well as with estrogenic stimulation."

May 1998 - May Ray Peat's Newsletter

Hormone levels and survival of prostate cancer patients

"Prostate cancer patients with higher LH levels and lower testosterone died the fastest. (Harper et al., 1984.) Furthermore, a high testosterone-to-estradiol or testosterone-to-prolactin ratio was associated with better survival. (Rannikko et al., 1981.) When the factors were considered separately, patients with higher testosterone levels had a better prognosis than those with lower levels, and patients with lower growth hormone levels fared better than those with higher growth hormone levels. (Wilson et al., 1985.)"

May 1998 - May Ray Peat's Newsletter

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